Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802482 | 0.76 | SLC13A5 (0.49) | HTR1AHTR2AHTR2CHTR2BHTR7 | |
| SCHEMBL25795552 | 0.75 | NOS3 (0.39) | — | |
| SCHEMBL24802437 | 0.72 | GAA (0.35) | HTR2B | |
| SCHEMBL25246536 | 0.72 | HTR6 (0.48) | HTR1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL30566012 | 0.72 | HTR6 (0.48) | HTR1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL21459479 | 0.71 | HTR7 (0.37) | HTR1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL10949866 | 0.70 | AMY1A (0.52) | HTR1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL30148591 | 0.69 | HTR2A (0.49) | HTR1AHTR2AHTR2CHTR2BHTR7 | |
| SCHEMBL29038139 | 0.68 | HTR2A (0.40) | HTR1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL21459468 | 0.66 | HTR2A (0.41) | HTR1AHTR2AHTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |