Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PCNA | P12004 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802457 | 0.80 | SLC13A5 (0.49) | GAASLC13A5GRIN2BSLC13A2SLC13A3 | |
| SCHEMBL25795552 | 0.76 | NOS3 (0.39) | GAASLC13A5KDM4EGABRA1HPGD | |
| SCHEMBL25680862 | 0.73 | GABRA1 (0.36) | GAAGRIN2BGRIN1HSD17B10KDM4E | |
| SCHEMBL24802456 | 0.72 | AMY1A (0.49) | GAAHSD17B10PCNAKDM4ELMNA | |
| SCHEMBL24802441 | 0.72 | HTR1A (0.40) | HTR2B | |
| SCHEMBL24802483 | 0.72 | POLB (0.48) | GAAGRIN2BHPGD | |
| SCHEMBL27500492 | 0.70 | TAAR1 (0.44) | HSD17B10KDM4ELMNAALBCYP3A4 | |
| SCHEMBL6583906 | 0.69 | SRC (0.44) | HSD17B10PCNAKDM4ELMNAALB | |
| SCHEMBL24802543 | 0.68 | GAA (0.39) | GAAHSD17B10KDM4ELMNAALB | |
| SCHEMBL3823395 | 0.68 | PCNA (0.43) | GRIN2BGRIN1HSD17B10PCNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |