Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480310 | 1.00 | TRPA1 (0.37) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL19576454 | 0.78 | TRPA1 (0.43) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL8428375 | 0.76 | TRPA1 (0.42) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL8428377 | 0.76 | TRPA1 (0.42) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL2483434 | 0.76 | GAA (0.32) | GAAMETAP2 | |
| SCHEMBL2483436 | 0.76 | GAA (0.32) | GAAMETAP2 | |
| SCHEMBL7738653 | 0.71 | TRPA1 (0.48) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL2477284 | 0.70 | TSHR (0.39) | TRPA1TRPM8 | |
| SCHEMBL19566541 | 0.70 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL28907747 | 0.69 | METAP2 (0.35) | TRPA1GAAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376411-B1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO PERFUMERY CO LTD (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-8580991-B2 | Aluminium complexes and use thereof as a catalyst in intramolecular ring closure reactions | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20110319638-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110257412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2376412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | Takasago International Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| EP-2376411-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | Takasago International Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010071231-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010071227-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257412-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | C9, NFE2L2, ALOX12 | TRPA1 376/4885TRPM8 3103/4885CA1 315/4885 |
| US-20110319638-A1 | ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS | LEF1, AP1M1, C9 | TRPA1 884/4885TRPM8 3538/4885CA1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.