SCHEMBL2480377

SCHEMBL2480377

CC(C)(C)OC(=O)N1CCN(c2c(F)cc(N3C(=O)OCC3CN)cc2F)CC1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.40
DPP4 P27487 1/20 0.39
MMP2 P08253 1/20 0.39
MMP13 P45452 1/20 0.39
MMP14 P50281 1/20 0.39
ADAMTS5 Q9UNA0 1/20 0.39
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
PDK2 Q15119 1/20 0.36
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
KDM4E B2RXH2 1/20 0.35
THRB P10828 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2507043 0.91 GPR119 (0.41) GPR119DPP4MMP2MMP13MMP14
SCHEMBL2499942 0.87 GPR119 (0.39) GPR119
SCHEMBL2452755 0.87 MAOA (0.40) GPR119DPP4MMP2MMP13MMP14
SCHEMBL2498576 0.86 HPGD (0.39) GPR119DPP4MAPTALDH1A1LMNA
SCHEMBL2503392 0.86 GPR119 (0.37) GPR119DPP4MMP2MMP13MMP14
SCHEMBL2486343 0.85 GPR119 (0.37) GPR119DPP4MMP2MMP13MMP14
SCHEMBL2480116 0.85 ALDH1A1 (0.37) GPR119DPP4MAPTALDH1A1LMNA
SCHEMBL2501461 0.83 MAOA (0.38) GPR119MAOA
SCHEMBL2502268 0.82 GPR119 (0.38) GPR119MMP2MMP13MMP14ADAMTS5
SCHEMBL2501176 0.81 KDM1A (0.40) GPR119ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841306-B2 Antimicrobials PANACEA BIOTEC LTD. (IN) 2014-09-23 US disclosed
US-20110245258-A1 NOVEL ANTIMICROBIALS PANACEA BIOTEC LTD. (IN) 2011-10-06 US disclosed
EP-2367820-A2 Novel antimicrobials Panacea Biotec Limited (IN) 2011-09-28 EP disclosed
WO-2010058423-A2 NOVEL ANTIMICROBIALS PANACEA BIOTEC LTD. (IN) 2010-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245258-A1 NOVEL ANTIMICROBIALS ECI1, XDH, CYP3A4 GPR119 2490/4885DPP4 436/4885MMP2 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.