Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15139146 | 0.79 | NPSR1 (0.42) | HPGDALDH1A1NPSR1RXFP1KMT2A | |
| SCHEMBL167135 | 0.75 | RAF1 (0.45) | RAF1L3MBTL1MAPK14 | |
| SCHEMBL23385631 | 0.71 | ALDH1A1 (0.38) | RAF1SMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL23385728 | 0.71 | PKM (0.34) | SMN1; SMN2HPGDALDH1A1NPC1NPSR1 | |
| SCHEMBL13785260 | 0.68 | MAPK14 (0.52) | HPGDALDH1A1KMT2AMAPK14 | |
| SCHEMBL14100165 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL12265897 | 0.67 | YEATS4 (0.51) | RAF1SMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL4404284 | 0.66 | TDP1 (0.46) | SMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL21727182 | 0.66 | ALDH1A1 (0.36) | RAF1SMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL13637071 | 0.65 | YEATS4 (0.40) | HPGDALDH1A1NPSR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411392-A1 | Amide Derivative And Preparation Method Therefore And Use Thereof In Medicine | CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411392-A1 | Amide Derivative And Preparation Method Therefore And Use Thereof In Medicine | NLRP3, NLRP1, PYCARD | RAF1 2638/4885SMN1; SMN2 4176/4885HPGD 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.