Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807366 | 0.84 | KIF11 (0.45) | RXRARXRBRXRGPTPN5HDAC8 | |
| SCHEMBL276759 | 0.84 | HDAC8 (0.59) | RXRARXRBRXRGKAT6AHDAC8 | |
| SCHEMBL25614809 | 0.82 | AKR1C3 (0.46) | RXRARXRBRXRGHSD17B1HSD17B2 | |
| SCHEMBL19369014 | 0.80 | CRBN (0.54) | RXRARXRBRXRGPTPN5HDAC8 | |
| SCHEMBL1004004 | 0.80 | HDAC8 (0.43) | KAT6AHDAC8HDAC6CDK8KDM4E | |
| SCHEMBL26378227 | 0.77 | BRAF (0.49) | RXRARXRBRXRGPTPN5 | |
| SCHEMBL13702375 | 0.76 | HDAC8 (0.68) | HDAC8HDAC6CDK8CRBNCYP3A4 | |
| SCHEMBL8676319 | 0.76 | RXRA (0.56) | RXRARXRBRXRGPTPN5HDAC8 | |
| SCHEMBL4602193 | 0.76 | RXRA (0.78) | RXRARXRBRXRGPTPN5 | |
| SCHEMBL24726523 | 0.75 | RXRA (0.58) | RXRARXRBRXRGCDK8CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271970-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |