Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807366 | 0.91 | KIF11 (0.45) | AKR1C3HSD17B1HSD17B2RXRARXRB | |
| SCHEMBL14210413 | 0.85 | MMP13 (0.53) | AKR1C3MMP13HSD17B1HSD17B2RXRA | |
| SCHEMBL24809157 | 0.82 | RXRA (0.55) | HSD17B1HSD17B2RXRARXRBRXRG | |
| SCHEMBL12030869 | 0.80 | TAS1R3 (0.40) | MMP13SCN5ASCN2A | |
| SCHEMBL1004004 | 0.80 | HDAC8 (0.43) | MMP13 | |
| SCHEMBL16574182 | 0.76 | MMP13 (0.69) | MMP13 | |
| SCHEMBL19391346 | 0.75 | HDAC2 (0.53) | SCN5ASCN2AANPEP | |
| SCHEMBL14210412 | 0.74 | CRBN (0.58) | MMP13 | |
| SCHEMBL19369014 | 0.74 | CRBN (0.54) | RXRARXRBRXRG | |
| SCHEMBL20346989 | 0.74 | CA12 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |