Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25614809 | 0.91 | AKR1C3 (0.46) | HSD17B1HSD17B2ANPEPAKR1C3RXRA | |
| SCHEMBL19391346 | 0.84 | HDAC2 (0.53) | KIF11ANPEPHDAC6HDAC2HDAC8 | |
| SCHEMBL24809157 | 0.84 | RXRA (0.55) | HSD17B1HSD17B2RXRARXRBRXRG | |
| SCHEMBL19369014 | 0.83 | CRBN (0.54) | RXRARXRBRXRGHDAC6HDAC8 | |
| SCHEMBL1004004 | 0.82 | HDAC8 (0.43) | HDAC6HDAC2HDAC8 | |
| SCHEMBL105171 | 0.79 | HDAC6 (0.59) | HDAC6HDAC1HDAC2HDAC8CYP2C9 | |
| SCHEMBL20346989 | 0.76 | CA12 (0.39) | HDAC6HDAC2HDAC8 | |
| SCHEMBL12030869 | 0.76 | TAS1R3 (0.40) | HDAC6HDAC2HDAC8 | |
| SCHEMBL12026617 | 0.75 | CES2 (0.42) | ANPEPHDAC6HDAC2HDAC8 | |
| SCHEMBL3080949 | 0.74 | RXRA (0.57) | KIF11RXRARXRBRXRGAKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2022271970-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |