SCHEMBL2480932

SCHEMBL2480932

Cc1ccc(-c2cccc(-c3ccc(F)cc3)c2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
CYP2A6 P11509 1/20 0.50
MET P08581 2/20 0.47
CCR1 P32246 1/20 0.47
CCR5 P51681 1/20 0.47
CCR8 P51685 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
PIM1 P11309 2/20 0.46
AURKA O14965 1/20 0.46
ABL1 P00519 1/20 0.46
NTRK1 P04629 1/20 0.46
LCK P06239 1/20 0.46
CSF1R P07333 1/20 0.46
RET P07949 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46
FLT3 P36888 1/20 0.46
MAPK8 P45983 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3771686 0.98 CYP3A4 (0.49) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL12203428 0.89 HPGDS (0.54) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL2480995 0.86 CYP3A4 (0.56) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL503090 0.86 CYP3A4 (0.63) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL27687343 0.85 CYP3A4 (0.54) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL328396 0.85 HPGDS (0.56) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL2997318 0.84 CCR1 (0.60) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL12203899 0.82 CYP3A4 (0.45) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL12203789 0.82 CYP3A4 (0.45) CYP3A4CYP2A6METCCR1CCR5
SCHEMBL12797772 0.79 CYP3A4 (0.59) CYP3A4CYP2A6METCCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3428986-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2021-01-20 EP disclosed
EP-3428986-A1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2019-01-16 EP disclosed
EP-3428986-A1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2019-01-16 EP disclosed
EP-1763902-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-29 EP disclosed
US-8603645-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-12-10 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
US-20100176390-A1 ELECTROLUMINESCENT EFFICIENCY KWONG RAYMOND 2010-07-15 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed
US-20060008673-A1 Electroluminescent efficiency THE UNIVERSITY OF SOUTHERN CALIFORNIA 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060008673-A1 Electroluminescent efficiency EML4, LEF1, ESR1 CYP3A4 418/4885CYP2A6 1729/4885MET 2308/4885
US-20100176390-A1 ELECTROLUMINESCENT EFFICIENCY EML4, LEF1, ESR1 CYP3A4 305/4885CYP2A6 1310/4885MET 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.