SCHEMBL24809555

SCHEMBL24809555

Clc1cncc(-c2cccnc2Br)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
PTGS1 P23219 2/20 0.37
PTGS2 P35354 2/20 0.37
MKNK1 Q9BUB5 1/20 0.37
MKNK2 Q9HBH9 1/20 0.37
ROCK2 O75116 1/20 0.37
ROCK1 Q13464 1/20 0.37
CDC42BPB Q9Y5S2 1/20 0.37
S1PR4 O95977 1/20 0.37
GRM4 Q14833 1/20 0.37
FGFR1 P11362 1/20 0.36
NPY5R Q15761 1/20 0.36
PDE4A P27815 1/20 0.36
CYP2A6 P11509 3/20 0.35
PDK2 Q15119 1/20 0.35
LRRK2 Q5S007 1/20 0.34
AOC3 Q16853 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24809554 0.79 NUDT1 (0.45) S1PR4NPY5R
SCHEMBL10957005 0.77 CYP2A6 (0.55) CYP11B1CYP11B2PTGS2MKNK1MKNK2
SCHEMBL24809520 0.77 TDP1 (0.47) PTGS1PTGS2S1PR4
SCHEMBL7232205 0.73 METAP2 (0.49) CYP11B1CYP11B2PTGS1PTGS2MKNK1
SCHEMBL23501621 0.72 CYP2A6 (0.48) CYP11B1CYP11B2MKNK1MKNK2GRM4
SCHEMBL30416038 0.71 CYP2A6 (0.62) CYP11B1CYP11B2MKNK1MKNK2FGFR1
SCHEMBL27779502 0.70 HPGD (0.47) MKNK1MKNK2FGFR1
SCHEMBL1203598 0.70 ALDH1A1 (0.50) PTGS1PTGS2CYP2A6
SCHEMBL4197660 0.70 CNR2 (0.41) MKNK1MKNK2GRM4FGFR1NPY5R
SCHEMBL21744554 0.69 MKNK1 (0.55) CYP11B1CYP11B2PTGS2MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022267901-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT. AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-12-29 WO disclosed