SCHEMBL24809554

SCHEMBL24809554

Clc1cccc(-c2cccnc2Br)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 4/20 0.45
DHFR P00374 1/20 0.45
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43
GRM5 P41594 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TDO2 P48775 1/20 0.42
RORB Q92753 1/20 0.42
NOTUM Q6P988 1/20 0.42
MAP4K4 O95819 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
S1PR4 O95977 1/20 0.42
BACE1 P56817 1/20 0.42
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28827012 0.80 MAP4K4 (0.43) NPC1MAPTRAB9ASMN1; SMN2NOTUM
SCHEMBL24809520 0.79 TDP1 (0.47) RAB9ASMN1; SMN2MAP4K4S1PR4CYP19A1
SCHEMBL24809555 0.79 CYP11B1 (0.39) S1PR4NPY5R
SCHEMBL5666351 0.79 PIK3CD (0.53) MAP4K4ADORA1CYP19A1KDR
SCHEMBL3875933 0.79 CYP11B2 (0.55) NUDT1DHFRMAPTTDO2RORB
SCHEMBL7444875 0.77 BRD4 (0.52) NUDT1DHFRTP53MAPTTSHR
SCHEMBL1203598 0.77 ALDH1A1 (0.50) MAP4K4
SCHEMBL28404602 0.76 NUDT1 (0.51) NUDT1DHFRTDO2RORBADORA2A
SCHEMBL15676581 0.75 LOXL2 (0.47) NUDT1DHFRNPC1MAPTRAB9A
SCHEMBL4819319 0.75 PDE4A (0.44) MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022267901-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT. AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-12-29 WO disclosed