Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811366 | 0.88 | TSHR (0.38) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL25793571 | 0.86 | TSHR (0.43) | MEN1KMT2ATSHRSMN1; SMN2CASP2 | |
| SCHEMBL25793735 | 0.82 | HPGD (0.40) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL25791257 | 0.80 | TP53 (0.41) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL24813893 | 0.79 | TSHR (0.40) | MEN1KMT2ATSHRSMN1; SMN2CASP2 | |
| SCHEMBL20469919 | 0.77 | CASP2 (0.42) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL26482295 | 0.77 | MEN1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24982536 | 0.77 | MEN1 (0.40) | KDM4EMEN1KMT2ATSHRCASP2 | |
| SCHEMBL24615974 | 0.77 | HPGD (0.40) | ALDH1A1MEN1KMT2AHTTTSHR | |
| SCHEMBL25791250 | 0.75 | TSHR (0.39) | KDM4EALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |