Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 15/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477910 | 0.88 | TMEM97 (0.42) | — | |
| SCHEMBL2477280 | 0.86 | SLC6A2 (0.47) | SLC6A3SLC6A4 | |
| SCHEMBL2476151 | 0.85 | TACR3 (0.40) | TACR3SLC6A4TACR1 | |
| SCHEMBL2481589 | 0.83 | RORC (0.41) | TACR3SLC6A4TACR1 | |
| SCHEMBL2477444 | 0.80 | TACR3 (0.68) | TACR3TACR2TACR1 | |
| SCHEMBL2477851 | 0.80 | TACR3 (0.68) | TACR3TACR2TACR1 | |
| SCHEMBL2474721 | 0.78 | TACR3 (0.67) | TACR3TACR2TACR1 | |
| SCHEMBL3742127 | 0.77 | SLC6A3 (0.46) | TACR3SLC6A3SLC6A4 | |
| SCHEMBL5792422 | 0.75 | SLC6A4 (0.47) | TACR3SLC6A3SLC6A4 | |
| N-Benzylmethylamine SCHEMBL2477187 | 0.75 | SLC6A4 (0.46) | TACR3SLC6A3SLC6A4TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | disclosed |