Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477280 | 0.92 | SLC6A2 (0.47) | SLC6A2 | |
| SCHEMBL2481589 | 0.88 | RORC (0.41) | SLC6A2 | |
| SCHEMBL2481591 | 0.88 | TACR3 (0.41) | — | |
| SCHEMBL2476151 | 0.85 | TACR3 (0.40) | SLC6A2 | |
| SCHEMBL5789157 | 0.75 | TMEM97 (0.42) | TMEM97SIGMAR1 | |
| SCHEMBL3742011 | 0.75 | TMEM97 (0.42) | TMEM97SIGMAR1 | |
| SCHEMBL5791992 | 0.73 | SIGMAR1 (0.58) | TMEM97SIGMAR1 | |
| N-Benzylmethylamine SCHEMBL2477549 | 0.73 | SLC6A4 (0.44) | TMEM97SIGMAR1SLC6A2 | |
| SCHEMBL17735432 | 0.71 | SLC6A4 (0.56) | SLC6A2 | |
| SCHEMBL2477546 | 0.71 | TACR3 (0.55) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | disclosed |