Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696642 | 0.89 | KMT2A (0.59) | GAAELANELMNAKMT2AALDH1A1 | |
| SCHEMBL11595637 | 0.85 | GAA (0.45) | GAACYP19A1ELANELMNAKMT2A | |
| SCHEMBL13842309 | 0.84 | GAA (0.47) | GAACYP19A1ELANELMNAKMT2A | |
| SCHEMBL16326823 | 0.83 | ALDH1A1 (0.46) | GAACYP19A1ELANELMNAKMT2A | |
| SCHEMBL28001930 | 0.83 | ALDH1A1 (0.55) | GAACYP19A1ELANELMNAKMT2A | |
| SCHEMBL18087017 | 0.83 | LMNA (0.53) | GAAELANELMNAKMT2AALDH1A1 | |
| SCHEMBL27283394 | 0.83 | LMNA (0.66) | GAALMNAKMT2AALDH1A1MAPT | |
| SCHEMBL11437247 | 0.83 | CYP19A1 (0.52) | GAACYP19A1ELANELMNAKMT2A | |
| SCHEMBL472034 | 0.81 | ALOX15 (0.65) | GAACYP19A1LMNAKMT2AALDH1A1 | |
| SCHEMBL27837444 | 0.81 | CYP19A1 (0.50) | GAACYP19A1ELANELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350301-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2014-11-27 | — | — | US | claimed |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2013-06-27 | — | — | US | claimed |
| EP-0425650-A1 | ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES. | FISONS PLC (GB) | 1991-05-08 | — | — | EP | claimed |
| WO-1990014338-A1 | ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES | FISONS PLC (GB) | 1990-11-29 | — | — | WO | claimed |
| CN-115746003-B | Methods of making and using PDE9 inhibitors | 卡都瑞恩医药公司 | 2024-08-09 | — | — | CN | disclosed |
| US-20240254366-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD OF MANUFACTURING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2024-08-01 | — | — | US | disclosed |
| EP-4284854-A1 | REPROCESSABLE COMPOSITIONS | Massachusetts Institute of Technology (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3406684-B1 | POLISHING COMPOSITION AND METHOD FOR POLISHING SILICON SUBSTRATE | FUJIMI INC (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-11702570-B2 | Polishing composition | FUJIMI INCORPORATED (JP) | 2023-07-18 | — | — | US | disclosed |
| US-11695155-B2 | Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20230155178-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-05-18 | — | — | US | disclosed |
| WO-2022256480-A1 | ARYLCOUMARIN SYNTHESIS WITH AZEOTROPIC REMOVAL OF WATER | CONAGEN INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| EP-0394101-B1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041403-A | Magnesium, titanium, halogen, ester compound, and organic aluminum compound | SHOWA DENKO K.K. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0394101-A1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-10-24 | — | — | EP | disclosed |
| EP-0383346-A2 | Catalyst, process for its preparation and process for polymerization of olefins using this catalyst | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-08-22 | — | — | EP | disclosed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4040992-A | USING N-HYDROXYALKYL QUATERNARY AMMONIUM CARBONYLATE SALTS AS CATALYSTS; POLYURETHANES, POLYISOCYANURATES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11695155-B2 | Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same | PTPN1, TP53RK, VDAC1 | GAA 3551/4885CYP19A1 1192/4885ELANE 869/4885 |
| US-20140350301-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | THPO, P2RY4, TBXA2R | GAA 1682/4885CYP19A1 3235/4885ELANE 4586/4885 |
| US-20230155178-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME | PTPN1, TP53RK, VDAC1 | GAA 3551/4885CYP19A1 1192/4885ELANE 869/4885 |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | THPO, P2RY4, TBXA2R | GAA 1682/4885CYP19A1 3235/4885ELANE 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.