Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818937 | 0.89 | TRPV3 (0.33) | — | |
| SCHEMBL24821953 | 0.86 | ESR1 (0.35) | — | |
| SCHEMBL24818926 | 0.80 | HPGD (0.38) | KDM4EALDH1A1THRB | |
| SCHEMBL24818909 | 0.80 | ESR1 (0.33) | — | |
| SCHEMBL24819863 | 0.79 | CD274 (0.39) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29189910 | 0.76 | CD274 (0.39) | CD274PDCD1PDCD1LG2KDM4EALDH1A1 | |
| SCHEMBL29189912 | 0.76 | CD274 (0.39) | CD274PDCD1PDCD1LG2KDM4EALDH1A1 | |
| SCHEMBL24818935 | 0.73 | S1PR1 (0.34) | — | |
| SCHEMBL24818932 | 0.73 | KDM4E (0.40) | CD274PDCD1KDM4EALDH1A1 | |
| SCHEMBL30152637 | 0.72 | CBLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |