Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.34 |
| ▸ | CBLB | Q13191 | 7/20 | 0.32 |
| ▸ | CBL | P22681 | 6/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24821953 | 0.86 | ESR1 (0.35) | CBLBCBLESR1ESR2 | |
| SCHEMBL24818937 | 0.86 | TRPV3 (0.33) | CBLB | |
| SCHEMBL24818936 | 0.86 | CBL (0.32) | CBLBCBL | |
| SCHEMBL24820656 | 0.85 | CETP (0.33) | S1PR1S1PR3CBLBCBLESR2 | |
| SCHEMBL30153109 | 0.81 | CBLB (0.53) | CBLBCBL | |
| SCHEMBL24820655 | 0.78 | CBLB (0.41) | CBLBCBL | |
| SCHEMBL24819786 | 0.77 | S1PR1 (0.37) | S1PR1S1PR3CBLBESR1ESR2 | |
| SCHEMBL30153127 | 0.77 | S1PR1 (0.37) | S1PR1S1PR3CBLBESR1ESR2 | |
| SCHEMBL24818674 | 0.74 | VSIR (0.40) | S1PR1S1PR3CBLBCETP | |
| SCHEMBL24818926 | 0.74 | HPGD (0.38) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |