Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CBL | P22681 | 1/20 | 0.30 |
| ▸ | CBLB | Q13191 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818936 | 0.86 | CBL (0.32) | CBLCBLB | |
| SCHEMBL24818926 | 0.86 | HPGD (0.38) | ESR1ESR2HPGD | |
| SCHEMBL24821953 | 0.85 | ESR1 (0.35) | ESR1ESR2PDE4CHPGDCHRM2 | |
| SCHEMBL24818910 | 0.80 | CD274 (0.35) | — | |
| SCHEMBL24820656 | 0.76 | CETP (0.33) | ESR2HPGDCBLCBLB | |
| SCHEMBL24818927 | 0.75 | DRD2 (0.31) | CBLCBLB | |
| SCHEMBL24818935 | 0.74 | S1PR1 (0.34) | ESR1ESR2CBLCBLB | |
| SCHEMBL24818930 | 0.73 | SMN1; SMN2 (0.35) | ESR1ESR2PDE4CHPGD | |
| SCHEMBL24818937 | 0.69 | TRPV3 (0.33) | CBLB | |
| SCHEMBL30153197 | 0.67 | CBLB (0.54) | CBLCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |