SCHEMBL2481925

SCHEMBL2481925

CC(C)C1=Cc2cccc(Br)c2C1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.38
PIM1 P11309 1/20 0.30
CSNK1A1 P48729 1/20 0.30
CDK5 Q00535 1/20 0.30
ROCK1 Q13464 1/20 0.30
DYRK1A Q13627 1/20 0.30
LRRK2 Q5S007 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953571 0.79 GABRA1 (0.39)
SCHEMBL1319720 0.75 TRPA1 (0.41) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL31359427 0.75 TRPA1 (0.41) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL5950996 0.74 TRPA1 (0.43) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2960350 0.72 TRPA1 (0.42) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2971904 0.71 TRPA1 (0.41) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2971532 0.70 TRPA1 (0.38) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2973265 0.70 TRPA1 (0.38) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2965178 0.70 TRPA1 (0.38) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2973787 0.70 TRPA1 (0.41) TRPA1PIM1CSNK1A1CDK5ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3702379-B1 PROPYLENE RANDOM COPOLYMER LG CHEMICAL LTD (KR) 2024-04-17 EP disclosed
CN-111433237-B Propylene random copolymer LG化学株式会社 2022-09-20 CN disclosed
US-11339234-B2 Propylene random copolymer LG CHEM, LTD. 2022-05-24 US disclosed
US-20200354492-A1 Propylene Random Copolymer LG CHEM, LTD. (KR) 2020-11-12 US disclosed
EP-3702379-A1 PROPYLENE RANDOM COPOLYMER LG CHEM, LTD. (KR) 2020-09-02 EP disclosed
CN-111433237-A Propylene random copolymer LG化学株式会社 2020-07-17 CN disclosed
EP-1963347-B1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2011-10-19 EP disclosed
EP-1963347-B1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2011-10-19 EP disclosed
US-7550544-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-06-23 US disclosed
US-7550544-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-06-23 US disclosed
US-7446216-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-04 US disclosed
US-7446216-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-04 US disclosed
US-7446216-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-04 US disclosed
EP-1963347-A1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2008-09-03 EP disclosed
WO-2007070041-A1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-06-21 WO disclosed
WO-2007070041-A1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-06-21 WO disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX TRPA1 736/4885PIM1 2877/4885CSNK1A1 1120/4885
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization AP2M1, AP1M1, CPNE4 TRPA1 1845/4885PIM1 1693/4885CSNK1A1 1058/4885
US-20200354492-A1 Propylene Random Copolymer PRUNE1, PIP5K1A, PIP5K1C TRPA1 4043/4885PIM1 14/4885CSNK1A1 3913/4885
US-11339234-B2 Propylene random copolymer PRUNE1, PIP5K1A, PIP5K1C TRPA1 4043/4885PIM1 14/4885CSNK1A1 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.