Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 7/20 | 0.33 |
| ▸ | THRB | P10828 | 7/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29821560 | 0.87 | NR4A1 (0.40) | PTGS2ALDH1A1LMNAMYCNR4A1 | |
| SCHEMBL23168839 | 0.86 | TSHR (0.50) | ALDH1A1CYP2C19GAACYP2C9TSHR | |
| SCHEMBL24822266 | 0.82 | PTGS2 (0.40) | PTGS2BRD9ALDH1A1CYP2C19LMNA | |
| SCHEMBL24820995 | 0.81 | MYC (0.35) | MYCNR4A1THRATHRBGRM5 | |
| SCHEMBL24819268 | 0.80 | KMT2A (0.46) | ALDH1A1CYP2C19CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL24821004 | 0.79 | DPP4 (0.34) | ALDH1A1MYCNR4A1GAACTSB | |
| SCHEMBL23168671 | 0.78 | LMNA (0.41) | PTGS2ALDH1A1LMNA | |
| SCHEMBL23168781 | 0.75 | FAAH (0.40) | MYCNR4A1THRATHRBCYP2C9 | |
| SCHEMBL23168964 | 0.74 | THRA (0.61) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23168666 | 0.73 | KDM4E (0.50) | ALDH1A1LMNAMYCNR4A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411400-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411400-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | THRB, TSHR, THRA | PTGS2 1229/4885BRD9 861/4885ALDH1A1 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.