Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24823213 | 0.86 | CNR2 (0.53) | GRIN1GRIN2AGRIN2BCNR2KDM4E | |
| SCHEMBL28316256 | 0.76 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2BKDM4E | |
| SCHEMBL4168685 | 0.75 | GRIN1 (0.44) | GRIN1GRIN2AGRIN2BGHSR | |
| SCHEMBL31160335 | 0.75 | KDM4E (0.61) | KDM4EHDAC1HDAC6 | |
| SCHEMBL28044712 | 0.75 | KDM4E (0.61) | KDM4EHDAC1HDAC6 | |
| SCHEMBL30632384 | 0.74 | PKM (0.58) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL24822498 | 0.72 | TSHR (0.53) | CNR2 | |
| SCHEMBL8758273 | 0.71 | MAOA (0.59) | GRIN1GRIN2AGRIN2BHDAC1HDAC6 | |
| SCHEMBL4381790 | 0.71 | HDAC6 (0.56) | CNR2KDM4EHDAC1HDAC6 | |
| SCHEMBL12602893 | 0.70 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2BCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |