Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24822425 | 0.86 | GRIN1 (0.59) | CNR2KDM4EHDAC6HDAC1GRIN1 | |
| SCHEMBL24822609 | 0.79 | GRIN1 (0.66) | POLBGRIN1GRIN2AGRIN2B | |
| SCHEMBL24822562 | 0.79 | ATM (0.42) | CNR2POLBHDAC6HDAC1 | |
| SCHEMBL25594457 | 0.77 | MAOA (0.55) | HDAC6HDAC1GRIN1GRIN2AGRIN2B | |
| SCHEMBL24822498 | 0.75 | TSHR (0.53) | CNR2POLBSMN1; SMN2LMNATSHR | |
| SCHEMBL11712442 | 0.73 | FABP4 (0.51) | HDAC6HDAC1GRIN1GRIN2AGRIN2B | |
| SCHEMBL31160335 | 0.72 | KDM4E (0.61) | KDM4EPOLBL3MBTL1HDAC6HDAC1 | |
| SCHEMBL28044712 | 0.72 | KDM4E (0.61) | KDM4EPOLBL3MBTL1HDAC6HDAC1 | |
| SCHEMBL24823211 | 0.71 | KMT2A (0.47) | POLBTHRBL3MBTL1HDAC6HDAC1 | |
| SCHEMBL4381790 | 0.71 | HDAC6 (0.56) | CNR2KDM4EHDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |