Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL2482687

CCCCOc1ccccc1Cl.OCCOCCO

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 8/20 0.59
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
TSHR P16473 2/20 0.50
CYP1A2 P05177 4/20 0.49
CYP2C19 P33261 4/20 0.49
CYP2C9 P11712 2/20 0.49
KCNH2 Q12809 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
CYP3A4 P08684 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 2/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794754 0.88 L3MBTL1 (0.66) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL30167630 0.88 L3MBTL1 (0.66) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL2482690 0.87 L3MBTL1 (0.71) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL10775846 0.86 L3MBTL1 (0.67) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL10775946 0.86 L3MBTL1 (0.67) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL43317 0.86 L3MBTL1 (0.67) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL11874439 0.83 L3MBTL1 (0.64) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL2094937 0.82 MEN1 (0.58) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL11662071 0.81 L3MBTL1 (0.62) L3MBTL1MAPTTDP1TSHRCYP1A2
SCHEMBL9440806 0.81 CYP1A2 (0.60) L3MBTL1MAPTTDP1TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310496-B1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA CORP (JP) 2006-12-06 EP claimed
US-6916939-B2 Process for the preparation of cyclic esters and method for purification of the same KUREHA KAGAKU KOGYO K.K. (JP) 2005-07-12 US claimed
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same KUREHA CORPORATION (JP) 2003-10-09 US claimed
EP-1310496-A1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-14 EP claimed
CN-116897151-A Process for producing glycolide 株式会社吴羽 2023-10-17 CN disclosed
CN-111741952-B Process for producing glycolide 株式会社吴羽 2023-06-09 CN disclosed
WO-2022196178-A1 METHOD FOR PRODUCING GLYCOLIDE 株式会社クレハ 2022-09-22 WO disclosed
CN-110072856-B Process for producing alpha-hydroxycarboxylic acid dimer cyclic ester 株式会社吴羽 2022-03-15 CN disclosed
CN-111741953-B Method for producing glycolide 株式会社吴羽 2021-05-28 CN disclosed
CN-111757873-A Method for producing glycolide 株式会社吴羽 2020-10-09 CN disclosed
CN-111741953-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
CN-111741952-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
US-20110263875-A1 Production Process of Glycolide KUREHA CORPORATION (JP) 2011-10-27 US disclosed
EP-2377858-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2011-10-19 EP disclosed
US-20100168446-A1 METHOD FOR PURIFICATION OF CYCLIC ESTER KUREHA CORPORATION (JP) 2010-07-01 US disclosed
EP-2128151-A1 METHOD FOR PURIFICATION OF CYCLIC ESTER Kureha Corporation (JP) 2009-12-02 EP disclosed
EP-1310496-B1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA CORP (JP) 2006-12-06 EP disclosed
US-6916939-B2 Process for the preparation of cyclic esters and method for purification of the same KUREHA KAGAKU KOGYO K.K. (JP) 2005-07-12 US disclosed
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same KUREHA CORPORATION (JP) 2003-10-09 US disclosed
EP-1310496-A1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same CEL, CETP, MCCC2 L3MBTL1 4166/4885MAPT 1560/4885TDP1 1365/4885
US-20110263875-A1 Production Process of Glycolide RPN2, RPN1, DDOST L3MBTL1 4701/4885MAPT 910/4885TDP1 3007/4885
US-20100168446-A1 METHOD FOR PURIFICATION OF CYCLIC ESTER MCCC2, CCDC47, HACD3 L3MBTL1 4388/4885MAPT 1567/4885TDP1 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.