SCHEMBL2482691

SCHEMBL2482691

Cc1cnc(N)c(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 9/20 0.48
NOS2 P35228 9/20 0.48
NOS1 P29475 6/20 0.48
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
UHRF1 Q96T88 1/20 0.37
MAP4K4 O95819 1/20 0.35
USP7 Q93009 1/20 0.34
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP2A6 P11509 1/20 0.33
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3190367 0.81 NOS3 (0.46) NOS3NOS2NOS1CCR1CCR5
SCHEMBL5809638 0.81 NOS3 (0.46) NOS3NOS2NOS1CCR1CCR5
SCHEMBL20822293 0.81 NOS3 (0.46) NOS3NOS2NOS1CCR1CCR5
SCHEMBL30684515 0.81 NOS3 (0.46) NOS3NOS2NOS1CCR1CCR5
Ammonia Solution, Strong SCHEMBL29016866 0.79 NOS3 (0.44) NOS3NOS2NOS1CCR1CCR5
Trifluoromethanesulfonic Acid SCHEMBL18796106 0.79 KCNH2 (0.34) NOS3NOS2NOS1MAP4K4KDM4E
SCHEMBL13879692 0.79 AGXT (0.55) NOS3NOS2NOS1USP7ALDH1A1
SCHEMBL142309 0.78 NOS3 (0.42) NOS3NOS2NOS1UHRF1MAP4K4
SCHEMBL30470000 0.78 NOS3 (0.42) NOS3NOS2NOS1UHRF1MAP4K4
SCHEMBL21206805 0.77 LMNA (0.44) NOS3NOS2NOS1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103103584-B Plating solution and coating method 罗门哈斯电子材料有限公司 2017-04-05 CN claimed
CN-103103584-A Plating bath and method ROHM & HAAS ELECT MAT 2013-05-15 CN claimed
US-20250127937-A1 FAP INHIBITOR UNIV HEIDELBERG (DE) 2025-04-24 US disclosed
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 EP disclosed
CN-115996926-A Indole compounds as androgen receptor modulators 尼多生物科学有限公司 2023-04-21 CN disclosed
US-20230112012-A1 FAP INHIBITOR UNIVERSITAT HEIDELBERG (DE) 2023-04-13 US disclosed
EP-3686199-B9 FUSED RING DERIVATIVE AS A2A RECEPTOR INHIBITOR CSTONE PHARMACEUTICALS SUZHOU CO LTD (CN) 2022-12-07 EP disclosed
CN-108473526-B Process for producing oligonucleotide and nucleoside, nucleotide or oligonucleotide 味之素株式会社 2022-08-09 CN disclosed
CN-113717239-A Precipitation accelerator and precipitation method using the same 味之素株式会社 2021-11-30 CN disclosed
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
US-20210038749-A1 FAP INHIBITOR Universität Heidelberg (DE) 2021-02-11 US disclosed
EP-2088861-A2 BENZIMIDAZOLE COMPOUNDS Takeda Pharmaceutical Company Limited (JP) 2009-08-19 EP disclosed
US-7528140-B2 Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors TEIJIN LIMITED (JP) 2009-05-05 US disclosed
US-7528140-B2 Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors TEIJIN LIMITED (JP) 2009-05-05 US disclosed
WO-2008051533-A2 BENZIMIDAZOLE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-05-02 WO disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed
EP-0517589-B1 Tachykinin derivatives, their preparation and pharmaceutical compositions containing them ADIR (FR) 1996-12-27 EP disclosed
CN-1042906-A The method for preparing the Quinolonecar boxylic acid intermediate PFIZER (US) 1990-06-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210038749-A1 FAP INHIBITOR FAP, APC, FIBP NOS3 4455/4885NOS2 4150/4885NOS1 3789/4885
US-20250127937-A1 FAP INHIBITOR FAP, APC, FIBP NOS3 4455/4885NOS2 4150/4885NOS1 3789/4885
US-20230112012-A1 FAP INHIBITOR FAP, APC, FIBP NOS3 4455/4885NOS2 4150/4885NOS1 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.