Phosphoric Acid

Phosphoric Acid

SCHEMBL2483057

CCCC[n+]1ccn(C)c1.O=P([O-])([O-])[O-].[H+].[H+]

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDPS P14324 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5449030 0.98 FDPS (0.43) FDPS
Methyl Phosphonate SCHEMBL21178429 0.95 FDPS (0.42) FDPS
SCHEMBL7529028 0.93 FDPS (0.41) FDPS
SCHEMBL1773792 0.93 FDPS (0.41) FDPS
Phosphoric Acid SCHEMBL28773844 0.93 FDPS (0.47) FDPS
Phosphoric Acid SCHEMBL6009687 0.93 FDPS (0.47) FDPS
SCHEMBL617158 0.93 FDPS (0.41) FDPS
SCHEMBL899069 0.93 FDPS (0.41) FDPS
SCHEMBL15922027 0.92 FDPS (0.40) FDPS
Phosphoric Acid SCHEMBL26092804 0.92 FDPS (0.46) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2558102-A1 SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS Davos Life Science Pte. Ltd. (SG) 2013-02-20 EP disclosed
US-20120136163-A1 Method for the Preparation of 1-Acetyl-6-Amino-3,3-Dimethyl-2,3-Dihydroindole AMGEN INC. (US) 2012-05-31 US disclosed
WO-2011129765-A1 SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS DAVOS LIFE SCIENCE PTE. LTD. (SG) 2011-10-20 WO disclosed
EP-2376448-A2 IMPROVED METHOD FOR THE PREPARATION OF 1-ACETYL-6-AMINO-3,3-DIMETHYL-2,3-DIHYDROINDOLE Amgen, Inc (US) 2011-10-19 EP disclosed
WO-2010071828-A2 IMPROVED METHOD FOR THE PREPARATION OF 1-ACETYL-6-AMINO-3,3-DIMETHYL-2,3-DIHYDROINDOLE AMGEN INC. (US) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136163-A1 Method for the Preparation of 1-Acetyl-6-Amino-3,3-Dimethyl-2,3-Dihydroindole AANAT, INMT, AADAT FDPS 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.