SCHEMBL24833948

SCHEMBL24833948

C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSC P53634 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ OPRD1 P41143 5/20 0.49
▸ OPRM1 P35372 4/20 0.49
▸ OPRK1 P41145 2/20 0.49
▸ POLB P06746 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ CTSS P25774 2/20 0.47
▸ CTSL P07711 1/20 0.47
▸ CTSB P07858 1/20 0.47
▸ CTSK P43235 1/20 0.47
▸ SLC7A5 Q01650 2/20 0.47
▸ MMP1 P03956 1/20 0.47
▸ MMP3 P08254 1/20 0.47
▸ MMP9 P14780 1/20 0.47
▸ METAP2 P50579 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ PTGS1 P23219 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30645049 1.00 CTSC (0.51) CTSCTDP1OPRD1OPRM1OPRK1
SCHEMBL30364805 0.97 OPRD1 (0.50) CTSCTDP1OPRD1OPRM1OPRK1
SCHEMBL30064540 0.94 OPRD1 (0.53) TDP1OPRD1OPRM1OPRK1ALDH1A1
SCHEMBL30064522 0.87 CTSD (0.53) CTSCOPRK1CTSSCTSLCTSB
SCHEMBL13135022 0.86 MAPT (0.57) CTSCOPRD1OPRM1OPRK1ALDH1A1
SCHEMBL9813890 0.85 POLB (0.57) TDP1POLBNPSR1MMP1MMP3
SCHEMBL10645951 0.84 OPRD1 (0.54) CTSCOPRD1OPRM1OPRK1CTSL
SCHEMBL2229345 0.84 METAP2 (0.60) CTSCOPRD1OPRM1OPRK1SLC7A5
SCHEMBL5497789 0.84 METAP2 (0.60) CTSCOPRD1OPRM1OPRK1SLC7A5
SCHEMBL1221379 0.83 SLC7A5 (0.58) TDP1POLBCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-10-09 — — US disclosed
EP-4538279-A2 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2025-04-16 — — EP disclosed
EP-4527846-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-03-26 — — EP disclosed
CN-119137136-A Dual-residue extension peptide and preparation method thereof 国立大学法人东海国立大学机构 2024-12-13 — — CN disclosed
US-20240368217-A1 PEPTIDE COMPOUND PRODUCTION METHOD AND AMIDATION AGENT CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-11-07 — — US disclosed
EP-4349848-A1 PEPTIDE COMPOUND PRODUCTION METHOD AND AMIDATION AGENT Chubu University Educational Foundation (JP) 2024-04-10 — — EP disclosed
WO-2023223714-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME 国立大学法人東海国立大学機構 2023-11-23 — — WO disclosed
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-01-05 — — US disclosed
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-01-05 — — US disclosed
WO-2022255195-A1 PEPTIDE COMPOUND PRODUCTION METHOD AND AMIDATION AGENT 学校法人中部大学 2022-12-08 — — WO disclosed
EP-4053132-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2022-09-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME NAAA, NOTUM, ASNS CTSC 2521/4885TDP1 4680/4885OPRD1 1465/4885
US-20240368217-A1 PEPTIDE COMPOUND PRODUCTION METHOD AND AMIDATION AGENT VIP, NPPA, IAPP CTSC 655/4885TDP1 4569/4885OPRD1 4206/4885
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NPPA, NGLY1, ANPEP CTSC 368/4885TDP1 4661/4885OPRD1 4270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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