SCHEMBL24835664

SCHEMBL24835664

CCc1cccc2nnoc12

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
ELANE P08246 7/20 0.40
MTNR1A P48039 6/20 0.34
MTNR1B P49286 6/20 0.34
KMT2A Q03164 1/20 0.32
KCNH2 Q12809 1/20 0.32
SCN5A Q14524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12355735 0.74 ELANE (0.35) ELANEKMT2A
SCHEMBL2620973 0.69 MTNR1A (0.57) GABRA1GABRB2ELANEMTNR1AMTNR1B
SCHEMBL28648952 0.69 GABRA1 (0.39) GABRA1GABRB2ELANEKMT2AKCNH2
SCHEMBL28187058 0.67 ELANE (0.45) GABRA1GABRB2ELANEMTNR1AMTNR1B
SCHEMBL11690968 0.65 GABRA1 (0.43) GABRA1GABRB2ELANEKCNH2SCN5A
SCHEMBL17853019 0.64 GABRA1 (0.52) GABRA1GABRB2ELANE
SCHEMBL22800127 0.64 SLC9A1 (0.46) GABRA1GABRB2ELANE
SCHEMBL25601983 0.64 SMN1; SMN2 (0.47) GABRA1GABRB2ELANEKMT2A
SCHEMBL23135919 0.63 ELANE (0.45) GABRA1GABRB2ELANEMTNR1AMTNR1B
SCHEMBL13296096 0.63 GABRA1 (0.50) GABRA1GABRB2ELANEKCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO INC (US) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT GABRA1 3517/4885GABRB2 3402/4885ELANE 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.