Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
| ▸ | BRAP | Q7Z569 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | USP16 | Q9Y5T5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487639 | 0.85 | HTR7 (0.34) | KMT2A | |
| SCHEMBL2482378 | 0.85 | — | — | |
| SCHEMBL417292 | 0.76 | TP53 (0.37) | RXFP1ALDH1A1PPARGTP53NPC1 | |
| SCHEMBL414416 | 0.72 | ACHE (0.48) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL417291 | 0.70 | L3MBTL1 (0.39) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL418468 | 0.70 | BCHE (0.43) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL414461 | 0.70 | ALDH1A1 (0.52) | ALDH1A1ADRB2NPC1RAB9AKMT2A | |
| SCHEMBL414460 | 0.70 | ACHE (0.51) | ALDH1A1LMNARAB9AKMT2ATDP1 | |
| SCHEMBL416337 | 0.70 | BCHE (0.43) | ALDH1A1KMT2ATDP1 | |
| SCHEMBL416610 | 0.69 | NPC1 (0.45) | ALDH1A1NPC1LMNARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |