Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.34 |
| ▸ | HTR1A | P08908 | 10/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483598 | 0.85 | RXFP1 (0.33) | KMT2A | |
| SCHEMBL2482378 | 0.77 | — | — | |
| SCHEMBL416317 | 0.70 | NCF1 (0.37) | HTR7HTR1AKMT2AHTR2CHTR2A | |
| SCHEMBL414416 | 0.70 | ACHE (0.48) | KMT2A | |
| SCHEMBL2487851 | 0.69 | SMN1; SMN2 (0.37) | HTR7HTR1AKMT2ADRD2DRD3 | |
| SCHEMBL414461 | 0.68 | ALDH1A1 (0.52) | KMT2A | |
| SCHEMBL414460 | 0.68 | ACHE (0.51) | KMT2A | |
| SCHEMBL2481990 | 0.66 | DRD2 (0.34) | HTR1AKMT2AHTR2ADRD2DRD3 | |
| SCHEMBL412451 | 0.65 | ACHE (0.54) | KMT2A | |
| SCHEMBL413455 | 0.65 | ACHE (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | claimed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | claimed |