Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.35 |
| ▸ | SRC | P12931 | 11/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 7/20 | 0.33 |
| ▸ | ABL2 | P42684 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
| ▸ | HCK | P08631 | 4/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | MTOR | P42345 | 4/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.32 |
| ▸ | PRKDC | P78527 | 4/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837548 | 1.00 | EGFR (0.35) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL19049955 | 0.73 | RET (0.38) | SRCPRMT5WDR77KDRTEK | |
| SCHEMBL29324056 | 0.72 | KDR (0.39) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL24837761 | 0.72 | PRMT5 (0.37) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL19402563 | 0.70 | AHCY (0.39) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL13067511 | 0.68 | SRC (0.42) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL19187882 | 0.67 | KDR (0.40) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL20058786 | 0.65 | PIK3CB (0.43) | EGFRSRCPRMT5WDR77ABL1 | |
| SCHEMBL19519734 | 0.63 | DYRK3 (0.46) | EGFRSRCABL1KDRHCK | |
| SCHEMBL22038311 | 0.62 | ADK (0.43) | EGFRSRCPRMT5ABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216414-A1 | Antiviral Agents and Nucleoside Analogs for Treatment of Zika Virus | UNIV EMORY (US) | 2024-07-04 | — | — | US | disclosed |
| US-20230000893-A1 | Antiviral Agents and Nucleoside Analogs for Treatment of Zika Virus | UNIV EMORY (US) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000893-A1 | Antiviral Agents and Nucleoside Analogs for Treatment of Zika Virus | SAMHD1, PNP, NUDT1 | EGFR 4525/4885SRC 2741/4885PRMT5 1461/4885 |
| US-20240216414-A1 | Antiviral Agents and Nucleoside Analogs for Treatment of Zika Virus | SAMHD1, PNP, NUDT1 | EGFR 4525/4885SRC 2741/4885PRMT5 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.