SCHEMBL2484307

SCHEMBL2484307

CCCCCO[SiH2]C(N)CC

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.36
OPRM1 P35372 1/20 0.34
CA1 P00915 9/20 0.34
CA2 P00918 9/20 0.34
CA9 Q16790 8/20 0.34
CA12 O43570 3/20 0.33
CA7 P43166 3/20 0.33
CA14 Q9ULX7 3/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
HTT P42858 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
HTR2C P28335 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27646914 0.75 DNM1 (0.35) DNM1OPRM1CA1CA2CA9
SCHEMBL6652373 0.74 DNM1 (0.36) DNM1CA1CA2CA9HTT
SCHEMBL761394 0.74 DNM1 (0.33) DNM1OPRM1CA1CA2CA9
SCHEMBL10356765 0.71 PRKD3 (0.34) DNM1CA1CA2CA9CA12
SCHEMBL11170038 0.71 CA2 (0.32) CA2
SCHEMBL23093205 0.70 ADRB2 (0.36) CA1CA2ADRB2ADRB1ADRB3
SCHEMBL27907010 0.70 DNM1 (0.36) DNM1OPRM1CA1CA2CA9
SCHEMBL3804031 0.69
SCHEMBL27626704 0.68 ADRB2 (0.35) ADRB2ADRB1ADRB3
SCHEMBL31563017 0.68 OPRM1 (0.38) DNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9623124-B2 Multimodal diagnostic technology for early stage cancer lesions NORTHEASTERN UNIVERSITY (US) 2017-04-18 US disclosed
EP-2549925-B1 Multimodal diagnostic technology for early stage cancer lesions UNIV NORTHEASTERN (US) 2015-10-21 EP disclosed
US-20130224120-A1 MULTIMODAL DIAGNOSTIC TECHNOLOGY FOR EARLY STAGE CANCER LESIONS NORTHEASTERN UNIVERSITY (US) 2013-08-29 US disclosed
EP-2549925-A1 MULTIMODAL DIAGNOSTIC TECHNOLOGY FOR EARLY STAGE CANCER LESIONS Northeastern University (US) 2013-01-30 EP disclosed
WO-2011119822-A1 MULTIMODAL DIAGNOSTIC TECHNOLOGY FOR EARLY STAGE CANCER LESIONS NORTHEASTERN UNIVERSITY (US) 2011-09-29 WO disclosed