SCHEMBL27907010

SCHEMBL27907010

CCCCCO[SiH2]C(C)CCCC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.36
OPRM1 P35372 1/20 0.34
PLA2G2C Q5R387 1/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31
USP2 O75604 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
CA12 O43570 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31563018 0.94 OPRM1 (0.38) DNM1OPRM1TSHRSPHK1THRB
SCHEMBL31563017 0.94 OPRM1 (0.38) DNM1OPRM1TSHRSPHK1THRB
SCHEMBL6652373 0.83 DNM1 (0.36) DNM1TSHRSPHK1USP2CA1
SCHEMBL27646914 0.79 DNM1 (0.35) DNM1OPRM1TSHRSPHK1USP2
SCHEMBL27626704 0.77 ADRB2 (0.35) TSHR
SCHEMBL8425703 0.75
SCHEMBL705012 0.73 ADRB2 (0.35) DNM1TSHRSMN1; SMN2
SCHEMBL1609561 0.72 DNM1 (0.38) DNM1PLA2G2CTSHRSMN1; SMN2
SCHEMBL706289 0.72
SCHEMBL10356765 0.71 PRKD3 (0.34) DNM1TSHRUSP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107841010-A Preparation method of easy-to-process reinforced styrene butadiene rubber 中国石油天然气股份有限公司 2018-03-27 CN claimed
CN-105985369-A Preparation method of silicon-loaded ion complexing agent 中国石油天然气股份有限公司 2016-10-05 CN claimed
CN-105985456-A Method for removing metal rhodium in hydrogenated nitrile rubber 中国石油天然气股份有限公司 2016-10-05 CN claimed
CN-105732907-A Preparation method of graft reinforced nitrile rubber 中国石油天然气股份有限公司 2016-07-06 CN claimed
CN-105732690-A Rubber reinforcing agent, preparation method thereof and preparation method of styrene butadiene rubber 中国石油天然气股份有限公司 2016-07-06 CN claimed
CN-105732689-A Rubber reinforcing agent, preparation method thereof and preparation method of reinforced nitrile rubber 中国石油天然气股份有限公司 2016-07-06 CN claimed
CN-104650291-A Method for preparing reinforced butadiene styrene rubber by olefin metathesis catalyst PETROCHINA CO LTD 2015-05-27 CN claimed
CN-104650130-A Method for preparing reactive reinforcing release agent by adopting olefin metathesis catalyst PETROCHINA CO LTD 2015-05-27 CN claimed
CN-103159892-B Preparation method of reinforced release agent CHINA NAT PETROLEUM CORP 2015-02-25 CN claimed
CN-103159866-B Preparation method of reinforced powdered rubber PETROCHINA CO LTD 2014-11-26 CN claimed
CN-103159892-A Preparation method of reinforced release agent CHINA NAT PETROLEUM CORP 2013-06-19 CN claimed
CN-103159866-A Preparation method of reinforced powdered rubber CHINA NAT PETROLEUM CORP 2013-06-19 CN claimed
CN-107841008-A Easily-processed reinforced styrene butadiene rubber and preparation method thereof 中国石油天然气股份有限公司 2018-03-27 CN disclosed
CN-107840902-A Preparation method of reinforcing plasticizer for nitrile rubber 中国石油天然气股份有限公司 2018-03-27 CN disclosed
CN-107841005-A Easily-processed reinforced nitrile rubber and preparation method thereof 中国石油天然气股份有限公司 2018-03-27 CN disclosed
CN-107840903-A Preparation method of reinforced softener for styrene butadiene rubber 中国石油天然气股份有限公司 2018-03-27 CN disclosed
CN-103159892-B Preparation method of reinforced release agent CHINA NAT PETROLEUM CORP 2015-02-25 CN disclosed
CN-103159866-B Preparation method of reinforced powdered rubber PETROCHINA CO LTD 2014-11-26 CN disclosed
CN-103159892-A Preparation method of reinforced release agent CHINA NAT PETROLEUM CORP 2013-06-19 CN disclosed
CN-103159866-A Preparation method of reinforced powdered rubber CHINA NAT PETROLEUM CORP 2013-06-19 CN disclosed