Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503144 | 1.00 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| SCHEMBL11480862 | 0.86 | GRIK1 (0.46) | GRIK1GRIK2ABATEP300FFAR1 | |
| SCHEMBL691600 | 0.83 | GRIK1 (0.50) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| SCHEMBL1003142 | 0.83 | GRIK1 (0.50) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| SCHEMBL9493661 | 0.83 | GRIK1 (0.50) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| Hydrochloric Acid SCHEMBL9624870 | 0.81 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| Ethylene Glycol SCHEMBL28971004 | 0.81 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3EP300 | |
| SCHEMBL10408349 | 0.81 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| SCHEMBL10408352 | 0.81 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3HDAC3 | |
| SCHEMBL10412636 | 0.81 | GRIK1 (0.48) | GRIK1GRIK2ABATFFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376053-B1 | POROUS POLYMER COATING FOR TOOTH WHITENING | JOHNSON & JOHNSON CONSUMER INC (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-109970997-A | A kind of preparation method of hydroxyethyl acrylate hydrogel | 安徽理工大学 | 2019-07-05 | — | — | CN | disclosed |
| US-9296846-B2 | Porous polymer coating for tooth whitening | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-8173159-B2 | Solid permeable shell of a polymer resin having surface modifying compounds that can react with isocyanates | SYNGENTA LIMITED (GB) | 2012-05-08 | — | — | US | disclosed |
| EP-2376053-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | McNeil-PPC, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010080501-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | MCNEIL-PPC, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100158960-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | KENVUE BRANDS LLC | 2010-06-24 | — | — | US | disclosed |
| US-7271200-B2 | Emulsions | SYNGENTA LIMITED (GB) | 2007-09-18 | — | — | US | disclosed |
| EP-1294478-B1 | NOVEL EMULSIONS | SYNGENTA LTD (GB) | 2005-12-28 | — | — | EP | disclosed |
| EP-1292386-B1 | NOVEL MICROCAPSULES | SYNGENTA LTD (GB) | 2005-11-16 | — | — | EP | disclosed |
| US-20040176479-A1 | Novel emulsions | SCHER HERBERT BENSON (US) | 2004-09-09 | — | — | US | disclosed |
| US-6710092-B2 | DISPERSED PHASE DROPLET HAVING SURFACTANT LAYER AT INTERFACE WITH CONTINUOUS PHASE WHEREIN SURFACTANT LAYER IS FORMED BY REACTION OF WALL-FORMING MOIETIES OF MICROCAPSULE WALL FORMING MATERIAL WITH INTERFACE MODIFYING COMPOUND | SYNGENTA LIMITED (GB) | 2004-03-23 | — | — | US | disclosed |
| EP-1294478-A2 | NOVEL EMULSIONS | Syngenta Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| EP-1292386-A2 | NOVEL MICROCAPSULES | Syngenta Limited (GB) | 2003-03-19 | — | — | EP | disclosed |
| US-20020136773-A1 | Novel microcapsules | SYNGENTA LIMITED (GB) | 2002-09-26 | — | — | US | disclosed |
| US-20020040065-A1 | Novel emulsions | SYNGENTA LIMITED (GB) | 2002-04-04 | — | — | US | disclosed |
| WO-2001094002-A2 | NOVEL EMULSIONS | SYNGENTA LIMITED (GB) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001094001-A2 | NOVEL MICROCAPSULES | SYNGENTA LIMITED (GB) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158960-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | MMP20, COL14A1, POLR1C | GRIK1 1492/4885GRIK2 1524/4885ABAT 4564/4885 |
| US-20020136773-A1 | Novel microcapsules | BPHL, CD68, RCC1 | GRIK1 1577/4885GRIK2 1043/4885ABAT 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.