Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457662 | 0.82 | KMT2A (0.36) | MAPTKMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL22031802 | 0.82 | KMT2A (0.36) | MAPTKMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL3843205 | 0.80 | KMT2A (0.52) | KMT2ALMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL2530689 | 0.79 | MAPT (0.38) | MAPTKMT2ALMNAPKMKDM4E | |
| SCHEMBL22654073 | 0.77 | GRM4 (0.38) | LMNACDK8ACVR1 | |
| SCHEMBL22031792 | 0.77 | CASR (0.40) | MAPTKMT2ALMNASMN1; SMN2CDK8 | |
| SCHEMBL22031838 | 0.77 | CDK8 (0.38) | MAPTLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL24252130 | 0.76 | L3MBTL1 (0.35) | MAPTKMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL25180336 | 0.75 | SMN1; SMN2 (0.40) | MAPTKMT2ALMNAPKMALDH1A1 | |
| SCHEMBL30388086 | 0.75 | SMN1; SMN2 (0.40) | MAPTKMT2ALMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379509-B1 | HERBICIDAL AND INSECTICIDAL PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER IP GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2379509-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | Bayer CropScience AG (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| WO-2010078912-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | MAPT 4507/4885KMT2A 1579/4885LMNA 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.