Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484646 | 0.79 | MAPT (0.44) | MAPTKMT2ALMNAPDE2APDE10A | |
| SCHEMBL29039033 | 0.70 | MAPT (0.51) | MAPTKMT2ALMNAPDE2APDE10A | |
| SCHEMBL22031793 | 0.69 | MEN1 (0.33) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL29457680 | 0.69 | MEN1 (0.33) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL18489287 | 0.68 | HTR1A (0.40) | KMT2AALDH1A1HPGD | |
| SCHEMBL22654071 | 0.67 | SMN1; SMN2 (0.31) | MAPTLMNACYP2C19 | |
| SCHEMBL29658208 | 0.67 | SMN1; SMN2 (0.31) | MAPTLMNACYP2C19 | |
| SCHEMBL24660438 | 0.66 | MAPK14 (0.40) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL29457681 | 0.66 | MAPK14 (0.40) | KMT2AMEN1PKMALDH1A1HPGD | |
| SCHEMBL12906071 | 0.64 | PDE5A (0.39) | LMNAPDE5AKDM4EALDH1A1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379509-B1 | HERBICIDAL AND INSECTICIDAL PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER IP GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2379509-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | Bayer CropScience AG (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100196714-A1 | PROCESS FOR PREPARING QUINOLINE COMPOUNDS AND PRODUCTS OBTAINED THEREFROM | WYETH (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| WO-2010078912-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | MAPT 4507/4885KMT2A 1579/4885LMNA 1586/4885 |
| US-20100196714-A1 | PROCESS FOR PREPARING QUINOLINE COMPOUNDS AND PRODUCTS OBTAINED THEREFROM | NNMT, QTRT1, HNMT | MAPT 1756/4885KMT2A 908/4885LMNA 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.