Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL444305 | 0.93 | APP (0.38) | APPEPHX2 | |
| SCHEMBL219270 | 0.91 | APP (0.37) | APP | |
| Potassium Ion SCHEMBL16009057 | 0.91 | APP (0.37) | APPEPHX2 | |
| SCHEMBL11973834 | 0.91 | APP (0.37) | APP | |
| Potassium Ion SCHEMBL11801333 | 0.91 | APP (0.37) | APPEPHX2 | |
| Lithium Ion SCHEMBL10598662 | 0.91 | APP (0.37) | APP | |
| SCHEMBL16010310 | 0.91 | APP (0.37) | APP | |
| Potassium Ion SCHEMBL16010564 | 0.91 | APP (0.37) | APPEPHX2 | |
| SCHEMBL17476621 | 0.91 | APP (0.37) | APP | |
| SCHEMBL10490320 | 0.89 | APP (0.35) | APPEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545090-B1 | RAFT AQUEOUS POLYMERIZATION OF BLOCK POLYMERS | UNIV SHEFFIELD (GB) | 2018-07-11 | — | — | EP | disclosed |
| US-9611335-B2 | Polymer synthesis | UNIVERSITY OF SHEFFIELD (GB) | 2017-04-04 | — | — | US | disclosed |
| US-20130046052-A1 | Polymer Synthesis | THE UNIVERSITY OF SHEFFIELD (GB) | 2013-02-21 | — | — | US | disclosed |
| EP-2545090-A2 | POLYMER SYNTHESIS | The University Of Sheffield (GB) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110841-A2 | POLYMER SYNTHESIS | THE UNIVERSITY OF SHEFFIELD (GB) | 2011-09-15 | — | — | WO | disclosed |