Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 4/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261104 | 0.79 | NPSR1 (0.48) | GBA1L3MBTL1PRKCIATRNPC1 | |
| SCHEMBL32682741 | 0.79 | NPSR1 (0.48) | GBA1L3MBTL1PRKCIATRNPC1 | |
| Hydrochloric Acid SCHEMBL5773639 | 0.78 | NPSR1 (0.46) | GBA1L3MBTL1PRKCIATRNPC1 | |
| SCHEMBL28150097 | 0.77 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL27669301 | 0.75 | PRKCI (0.50) | GBA1L3MBTL1PRKCIATRKDM4E | |
| SCHEMBL3979132 | 0.75 | RAB9A (0.55) | GBA1L3MBTL1NPC1KDM4ERAB9A | |
| SCHEMBL29642902 | 0.75 | RAB9A (0.55) | GBA1L3MBTL1NPC1KDM4ERAB9A | |
| Dimethylamine SCHEMBL4391998 | 0.73 | GBA1 (0.43) | GBA1L3MBTL1PRKCIATRNPC1 | |
| SCHEMBL1097431 | 0.73 | PRKCI (0.48) | GBA1L3MBTL1PRKCIATRALDH1A1 | |
| SCHEMBL65106 | 0.73 | ATR (0.53) | GBA1L3MBTL1PRKCIATRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866553-A | A kind of synthetic method of Favipiravir | 中南大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106866553-A | A kind of synthetic method of Favipiravir | 中南大学 | 2017-06-20 | — | — | CN | disclosed |
| EP-2376485-A1 | PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010071837-A1 | PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-06-24 | — | — | WO | disclosed |