Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32682741 | 1.00 | NPSR1 (0.48) | NPSR1PRKCIL3MBTL1ATRNPC1 | |
| Hydrochloric Acid SCHEMBL5773639 | 0.98 | NPSR1 (0.46) | NPSR1PRKCIL3MBTL1ATRNPC1 | |
| SCHEMBL71518 | 0.84 | NPSR1 (0.59) | NPSR1L3MBTL1TDP1KDM4EALDH1A1 | |
| Dimethylamine SCHEMBL4391998 | 0.81 | GBA1 (0.43) | PRKCIL3MBTL1ATRNPC1TDP1 | |
| SCHEMBL2484699 | 0.79 | GBA1 (0.44) | PRKCIL3MBTL1ATRNPC1TDP1 | |
| SCHEMBL29642902 | 0.79 | RAB9A (0.55) | L3MBTL1NPC1TDP1KDM4EALDH1A1 | |
| SCHEMBL3979132 | 0.79 | RAB9A (0.55) | L3MBTL1NPC1TDP1KDM4EALDH1A1 | |
| SCHEMBL9632764 | 0.78 | NPSR1 (0.52) | NPSR1L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL8934162 | 0.78 | NPC1 (0.39) | PRKCIL3MBTL1ATRNPC1TDP1 | |
| SCHEMBL361255 | 0.77 | KDM4E (0.58) | NPSR1L3MBTL1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 893 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264345-A | Porous adsorption resin for purifying silane and preparation method thereof | 成都至诚大公光电科技有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-117946013-B | Method for synthesizing 5, 6-dihalogen-3-aminopyrazine-2-methyl formate by one-pot method | 白银康寓信生物科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-117946013-A | Method for synthesizing 5, 6-dihalogen-3-aminopyrazine-2-methyl formate by one-pot method | 白银康寓信生物科技有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-105327609-A | Treating agent for removing three kinds of dioxin-like compounds in waste incineration waste off gas | CHEN YIJUN | 2016-02-17 | — | — | CN | claimed |
| CN-105327598-A | Treating method for removing three kinds of dioxin-like compounds in waste incineration waste off gas | CHEN YIJUN | 2016-02-17 | — | — | CN | claimed |
| CN-105037281-A | Preparation method for 3-(3-fluorophenoxyl)pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-105017166-A | Preparation method of 3-(3-bromine phenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOLOG TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | claimed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-102775358-A | Preparation method of 6-fluoro-3-hydroxy-2-pyrazinamide | SHANDONG QIDU PHARMACEUTICAL | 2012-11-14 | — | — | CN | claimed |
| JP-3066675-A | — | — | None | — | — | JP | disclosed |
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-115835909-B | Cannabinoid receptor type 2 (CB 2) modulators and uses thereof | 泰昂治疗公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20250270202-A1 | SUBSTITUTED 4-AMINOISOINDOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-08-28 | — | — | US | disclosed |
| EP-4373817-B1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2025-05-21 | — | — | EP | disclosed |
| US-RE30563-E | Preparation of benzoylureas | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4133956-A | Preparation of benzoylureas | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-3954753-A | SEDATIVES, MUSCLE RELAXANTS, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270202-A1 | SUBSTITUTED 4-AMINOISOINDOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | CUL4B, CUL3, CUL4A | NPSR1 2643/4885PRKCI 3588/4885L3MBTL1 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.