Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109735 | 0.73 | IDO1 (0.37) | MAOBGSTP1LMNACYP1A2PTGS1 | |
| SCHEMBL2068438 | 0.69 | LMNA (0.37) | MAOAMAOBL3MBTL1LMNACYP1A2 | |
| SCHEMBL6216372 | 0.63 | MAOB (0.63) | MAOAMAOBGSTP1PPARGNSD2 | |
| SCHEMBL2793853 | 0.63 | HPSE (0.45) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL13013400 | 0.63 | HPSE (0.45) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL25383684 | 0.63 | HPSE (0.45) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL10383431 | 0.63 | MAPT (0.53) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL25383688 | 0.63 | HPSE (0.45) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL6257581 | 0.63 | HPSE (0.45) | GSTP1PPARGNSD2ABL1RIN1 | |
| SCHEMBL13896928 | 0.63 | MAPT (0.53) | GSTP1PPARGNSD2ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000908-A1 | ENGINEERED CELLS AND USES THEREOF | OHIO STATE INNOVATION FOUNDATION | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000908-A1 | ENGINEERED CELLS AND USES THEREOF | CTSB, CTSL, CTSV | MAOA 3120/4885MAOB 1364/4885GSTP1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.