Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109735 | 0.76 | IDO1 (0.37) | LMNAIDO1PRKCAIDH1CYP1A2 | |
| SCHEMBL24848367 | 0.69 | MAOA (0.36) | LMNAALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL647501 | 0.61 | TRPA1 (0.48) | LMNAALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL3813606 | 0.61 | TRPA1 (0.48) | LMNAALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL647500 | 0.61 | TRPA1 (0.48) | LMNAALDH1A1HPGDTSHRMAPK1 | |
| Benzylphenylether SCHEMBL16443386 | 0.61 | LMNA (0.58) | LMNAMAOACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9406694 | 0.61 | LMNA (0.58) | LMNAMAOACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9406682 | 0.61 | LMNA (0.58) | LMNAMAOACYP1A2PTGS1SLC6A2 | |
| SCHEMBL21110938 | 0.59 | TYR (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7078672 | 0.59 | TYR (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2189452-B1 | ASCORBIC ACID DERIVATIVES AND SALTS THEREOF, PROCESS FOR THEIR PRODUCTION, AND COSMETIC PREPARATIONS THEREOF | SEIWA KASEI CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-8163939-B2 | Ascorbic acid derivative or salt thereof, production method thereof, and cosmetic | Seikwa Kasei Company, Limited (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20110059034-A1 | ASCORBIC ACID DERIVATIVE OR SALT THEREOF, PRODUCTION METHOD THEREOF, AND COSMETIC | SEIWA KASEI COMPANY, LIMITED (JP) | 2011-03-10 | — | — | US | disclosed |
| EP-2189452-A1 | ASCORBIC ACID DERIVATIVE OR SALT THEREOF, METHOD FOR PRODUCING THE SAME, AND COSMETIC PREPARATION | Seiwa Kasei Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059034-A1 | ASCORBIC ACID DERIVATIVE OR SALT THEREOF, PRODUCTION METHOD THEREOF, AND COSMETIC | CYP2R1, CYP24A1, RARA | LMNA 1946/4885ALDH1A1 89/4885HPGD 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.