SCHEMBL24849923

SCHEMBL24849923

CCC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 12/20 0.78
▸ AGTR2 P50052 2/20 0.77
▸ AGTR1 P30556 1/20 0.77
▸ LNPEP Q9UIQ6 5/20 0.71
▸ ANPEP P15144 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619763 0.94 AGTR1 (0.75) RENAGTR2AGTR1LNPEPANPEP
Angiotensin Iv SCHEMBL27169570 0.93 LNPEP (0.82) RENAGTR2AGTR1LNPEPANPEP
Angiotensin Iv SCHEMBL10066237 0.93 LNPEP (0.82) RENAGTR2AGTR1LNPEPANPEP
SCHEMBL4738788 0.89 AGTR1 (0.69) RENAGTR2AGTR1LNPEPANPEP
SCHEMBL31332289 0.88 AGTR2 (0.91) RENAGTR2AGTR1LNPEP
SCHEMBL28485749 0.88 AGTR2 (0.94) AGTR2AGTR1
SCHEMBL29770563 0.88 LNPEP (0.74) RENAGTR2AGTR1LNPEPANPEP
SCHEMBL29394721 0.87 AGTR2 (1.00) AGTR2AGTR1
Angiotensin Ii SCHEMBL21811603 0.87 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL29619824 0.87 AGTR2 (0.94) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000943-A1 METHOD OF INDUCING SYNAPTOGENESIS BY ADMINISTERING ANGIOTENSIN AND ANALOGUES THEREOF Synaptogenix, Inc. (US) 2023-01-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000943-A1 METHOD OF INDUCING SYNAPTOGENESIS BY ADMINISTERING ANGIOTENSIN AND ANALOGUES THEREOF GAP43, SNAP29, SYNGR2 REN 53/4885AGTR2 79/4885AGTR1 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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