SCHEMBL29619763

SCHEMBL29619763

CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 3/20 0.75
▸ AGTR2 P50052 2/20 0.75
▸ LNPEP Q9UIQ6 5/20 0.73
▸ ANPEP P15144 2/20 0.73
▸ REN P00797 8/20 0.73
▸ SLC6A2 P23975 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849923 0.94 REN (0.78) AGTR1AGTR2LNPEPANPEPREN
Angiotensin Iv SCHEMBL27169570 0.93 LNPEP (0.82) AGTR1AGTR2LNPEPANPEPREN
Angiotensin Iv SCHEMBL10066237 0.93 LNPEP (0.82) AGTR1AGTR2LNPEPANPEPREN
SCHEMBL4738788 0.90 AGTR1 (0.69) AGTR1AGTR2LNPEPANPEPREN
SCHEMBL31332289 0.89 AGTR2 (0.91) AGTR1AGTR2LNPEPREN
SCHEMBL29770563 0.88 LNPEP (0.74) AGTR1AGTR2LNPEPANPEPREN
SCHEMBL29701255 0.88 SLC6A2 (0.63) AGTR1AGTR2LNPEPANPEPREN
Angiotensin Ii SCHEMBL31477824 0.87 AGTR2 (0.98) AGTR1AGTR2
Angiotensin Ii SCHEMBL21811603 0.86 AGTR2 (1.00) AGTR1AGTR2
Angiotensin Ii SCHEMBL29361852 0.86 AGTR2 (1.00) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691485-A1 MUCOSAL ADJUVANT Toyama Prefecture (JP) 2026-02-11 — — EP claimed
WO-2024204419-A1 MUCOSAL ADJUVANT 富山県 2024-10-03 — — WO claimed
US-20220160905-A1 FLUORINATION METHOD OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2022-05-26 — — US claimed
EP-4691485-A1 MUCOSAL ADJUVANT Toyama Prefecture (JP) 2026-02-11 — — EP disclosed
EP-4676563-A1 DEVICE AND METHOD FOR PURIFYING BODY FLUIDS BY REMOVING ANGIOTENSIN-SPECIFIC ANTIBODIES Klingenberg, Georg Jochen (DE) 2026-01-14 — — EP disclosed
EP-4021571-B1 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR TREATMENT OF SHOCK 4TEEN4 Pharmaceuticals GmbH (DE) 2025-10-08 — — EP disclosed
EP-4552649-A2 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR TREATMENT OF SHOCK 4TEEN4 Pharmaceuticals GmbH (DE) 2025-05-14 — — EP disclosed
US-20250000932-A1 DIAGNOSIS AND TREATMENT OF VASODILATORY SHOCK UNIVERSITY OF MARYLAND, BALTIMORE 2025-01-02 — — US disclosed
WO-2024233922-A2 PYRIDINE-PIPERAZINE-BASED SCAFFOLDS AS HIGHLY POTENT AND SELECTIVE NEUROLYSIN ACTIVATORS TEXAS TECH UNIVERSITY SYSTEM (US) 2024-11-14 — — WO disclosed
WO-2024204419-A1 MUCOSAL ADJUVANT 富山県 2024-10-03 — — WO disclosed
WO-2024188952-A1 DEVICE AND METHOD FOR PURIFYING BODY FLUIDS BY REMOVING ANGIOTENSIN-SPECIFIC ANTIBODIES KLINGENBERG GEORG JOCHEN (DE) 2024-09-19 — — WO disclosed
EP-4427767-A1 DEVICE AND METHOD FOR EXTRACORPOREAL BLOOD WASHING WITH SEPARATION OF ANGIOTENSIN-SPECIFIC ANTIBODIES Klingenberg, Georg (DE) 2024-09-11 — — EP disclosed
CN-116731181-B Anti-human CD10 protein rabbit monoclonal antibody and application thereof 武汉爱博泰克生物科技有限公司 2024-01-12 — — CN disclosed
CN-116731181-A Anti-human CD10 protein rabbit monoclonal antibody and application thereof 武汉爱博泰克生物科技有限公司 2023-09-12 — — CN disclosed
US-20220307065-A1 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR TREATMENT OF SHOCK 4TEEN4 Pharmaceuticals GmbH (DE) 2022-09-29 — — US disclosed
US-20220273757-A1 METHODS FOR ADMINISTERING ANGIOTENSIN II BY MONITORING RENIN LEVELS LA JOLLA PHARMA LLC (US) 2022-09-01 — — US disclosed
US-20220211798-A1 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR A TREATMENT WITH ANGIOTENSIN-RECEPTOR-AGONIST AND/OR A PRECURSOR THEREOF 4TEEN4 Pharmaceuticals GmbH (DE) 2022-07-07 — — US disclosed
EP-4021571-A1 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR TREATMENT OF SHOCK 4TEEN4 Pharmaceuticals GmbH (DE) 2022-07-06 — — EP disclosed
CN-114556100-A Therapy guidance and/or therapy monitoring for treatment of shock 4TEEN4制药有限公司 2022-05-27 — — CN disclosed
US-20220160905-A1 FLUORINATION METHOD OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2022-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160905-A1 FLUORINATION METHOD AFF2, AFF1, AFF4 AGTR1 2311/4885AGTR2 1687/4885LNPEP 2308/4885
US-20220211798-A1 THERAPY GUIDANCE AND/OR THERAPY MONITORING FOR A TREATMENT WITH ANGIOTENSIN-RECEPTOR-AGONIST AND/OR A PRECURSOR THEREOF DPP3, ACE, FABP3 AGTR1 5/4885AGTR2 9/4885LNPEP 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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