SCHEMBL248517

SCHEMBL248517

COc1cccc(C(C)=O)n1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.44
ALDH1A1 P00352 1/20 0.44
APLNR P35414 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
NNMT P40261 2/20 0.41
CYP1A2 P05177 2/20 0.40
BTK Q06187 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
MAPT P10636 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29858015 1.00 CTSA (0.44) CTSAALDH1A1APLNRTDP1POLB
SCHEMBL8866132 0.86 CTSA (0.45) CTSAALDH1A1APLNRTDP1POLB
SCHEMBL29527015 0.84 TDP1 (0.61) CTSAAPLNRTDP1POLBKDM4E
SCHEMBL17338 0.84 TDP1 (0.61) CTSAAPLNRTDP1POLBKDM4E
SCHEMBL2304053 0.82 NNMT (0.56) CTSAAPLNRTDP1POLBKDM4E
SCHEMBL875715 0.82 MAPT (0.55) CTSAALDH1A1APLNRKDM4EMEN1
SCHEMBL31264286 0.82 MAPT (0.55) CTSAALDH1A1APLNRKDM4EMEN1
SCHEMBL15019936 0.82 KDM4E (0.44) CTSAAPLNRTDP1POLBKDM4E
SCHEMBL2277413 0.82 TDP1 (0.59) CTSAAPLNRTDP1POLBKDM4E
Hydrochloric Acid SCHEMBL29133272 0.82 TDP1 (0.59) CTSAAPLNRTDP1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116540465-B Electrochromic ion storage layer film and preparation method thereof NINGBO MI RUO ELECTRONIC TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-116540465-A Novel electrochromic ion storage layer film and preparation method thereof 宁波祢若电子科技有限公司 2023-08-04 CN claimed
CN-104357504-A Cell catalysis for producing chirality methoxyl pyridine ethanol UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-02-18 CN claimed
WO-2013006000-A2 METHOD FOR DETECTING BREAST CANCER USING RESPIRATORY GAS 주식회사 알앤엘내츄럴 (KR) 2013-01-10 WO claimed
CN-116540465-B Electrochromic ion storage layer film and preparation method thereof NINGBO MI RUO ELECTRONIC TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN disclosed
CN-121471279-A Bidentate cobalt complex containing imidazo [1, 2-alpha ] pyridine group and preparation method and application thereof 郑州大学 2026-02-06 CN disclosed
US-20250243177-A1 sGC STIMULATORS CYCLERION THERAPEUTICS, INC. 2025-07-31 US disclosed
US-20240174683-A1 MAP4K1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-05-30 US disclosed
EP-4288437-A1 MAP4K1 INHIBITORS Bayer Aktiengesellschaft (DE) 2023-12-13 EP disclosed
CN-116987047-A Heterocyclic oxime compound, preparation method, application and composition thereof 贵州大学 2023-11-03 CN disclosed
WO-2023208986-A1 IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-02 WO disclosed
CN-116540465-A Novel electrochromic ion storage layer film and preparation method thereof 宁波祢若电子科技有限公司 2023-08-04 CN disclosed
US-7622471-B2 Pyrazole derivatives having a pyridazine and pyridine functionality DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-11-24 US disclosed
US-7622471-B2 Pyrazole derivatives having a pyridazine and pyridine functionality DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-11-24 US disclosed
WO-2009103879-A1 NOVEL NITROGEN-CONTAINING ORGANIC COMPOUNDS THAT CAN BE USED AS PRECURSOR OF A CATALYTIC COMPOSITION IFP (FR) 2009-08-27 WO disclosed
WO-2009103879-A1 NOVEL NITROGEN-CONTAINING ORGANIC COMPOUNDS THAT CAN BE USED AS PRECURSOR OF A CATALYTIC COMPOSITION IFP (FR) 2009-08-27 WO disclosed
US-20070105919-A1 adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-05-10 US disclosed
US-20070105919-A1 adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-05-10 US disclosed
US-20060128685-A1 Pyrazole derivative DAIICHI PHARMACEUTICAL CO., LTD., (JP) 2006-06-15 US disclosed
EP-1591443-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128685-A1 Pyrazole derivative PTGS1, PTGS2, PTGER1 CTSA 949/4885ALDH1A1 139/4885APLNR 4609/4885
US-20240174683-A1 MAP4K1 INHIBITORS MAP3K4, MAP4K4, MAP4K1 CTSA 1631/4885ALDH1A1 3841/4885APLNR 3263/4885
US-20070105919-A1 adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders ADORA2A, ADORA3, ADORA1 CTSA 2388/4885ALDH1A1 2843/4885APLNR 390/4885
US-20250243177-A1 sGC STIMULATORS GUCY1A1, PTGIS, GUCY1B1 CTSA 3079/4885ALDH1A1 1325/4885APLNR 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.