Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837455 | 0.68 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL22057713 | 0.68 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL6837117 | 0.66 | MAPT (0.36) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL10242630 | 0.65 | MAPT (0.41) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL6226055 | 0.65 | MAPT (0.41) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL6226053 | 0.65 | MAPT (0.41) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL24852911 | 0.63 | MAP1LC3B (0.44) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B | |
| SCHEMBL23609087 | 0.63 | POLB (0.35) | ALDH1A1MAPTHTTLMNACYP2C9 | |
| SCHEMBL24569535 | 0.62 | — | — | |
| SCHEMBL9955864 | 0.61 | MAP1LC3B (0.55) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002374-A1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| US-20230002374-A1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| EP-4055016-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2022-09-14 | — | — | EP | disclosed |
| CN-114650992-A | GPR52 modulator compounds | 赫普泰雅治疗有限公司 | 2022-06-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002374-A1 | GPR52 MODULATOR COMPOUNDS | GPR52, GPR119, GPR4 | SMN1; SMN2 2536/4885ALDH1A1 1435/4885L3MBTL1 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.