Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486006 | 1.00 | SLC22A1 (0.47) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL5382965 | 0.78 | CA2 (0.48) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5382962 | 0.78 | CA2 (0.48) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2483578 | 0.76 | TAAR1 (0.51) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL2483579 | 0.76 | TAAR1 (0.51) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL16415896 | 0.75 | MAP1LC3B (0.43) | MAOASMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL16415897 | 0.75 | MAP1LC3B (0.43) | MAOASMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL14543883 | 0.75 | SLC22A1 (0.46) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL5379894 | 0.72 | CA12 (0.54) | SMN1; SMN2ALDH1A1CYP1A2LMNATSHR | |
| SCHEMBL5379889 | 0.72 | CA12 (0.54) | SMN1; SMN2ALDH1A1CYP1A2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017358-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | claimed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | claimed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | claimed |
| EP-3212183-B1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIV ROCHESTER (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10028931-B2 | Synergistic compositions for treating microbial infections | UNIVERSITY OF ROCHESTER (US) | 2018-07-24 | — | — | US | disclosed |
| EP-3212183-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | University of Rochester (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2017-08-31 | — | — | US | disclosed |
| WO-2016070021-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-05-06 | — | — | WO | disclosed |
| US-8778631-B2 | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system | SUTRO BIOPHARMA, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-2376647-B1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA INC (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2379578-A1 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD | Sutro Biopharma, Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20100184135-A1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184134-A1 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD | SUTRO BIOPHARMA, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010081110-A1 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD | SUTRO BIOPHARMA, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| WO-2010081111-A1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| EP-1017358-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | disclosed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028931-B2 | Synergistic compositions for treating microbial infections | RNASE1, RNASEL, RNASEH1 | SLC22A1 4066/4885HTR1A 4654/4885ADRA2A 4746/4885 |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | RNASE1, RNASEL, RNASEH1 | SLC22A1 4066/4885HTR1A 4654/4885ADRA2A 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.