SCHEMBL248605

SCHEMBL248605

C=CC(N)c1ccccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 1/20 0.45
KCNA5 P22460 5/20 0.40
KCNE1 P15382 2/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
PI4KA P42356 1/20 0.38
PI4K2B Q8TCG2 1/20 0.38
PI4K2A Q9BTU6 1/20 0.38
PI4KB Q9UBF8 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420495 0.79 SLC6A3 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL702427 0.79 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL6160196 0.78 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL11800360 0.78 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL5987168 0.76
SCHEMBL4954290 0.75 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL10945061 0.75 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL11034374 0.75 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL21742323 0.75 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL253431 0.75 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNA5KCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756841-A Preparation method and application of two-dimensional aromatic D-J type halide perovskite with photocatalytic activity 华东理工大学 2024-03-26 CN claimed
CN-117362259-A 6-azo phenyl coumarin-3-formamide compound, and preparation method and application thereof 南京林业大学 2024-01-09 CN claimed
CN-117229523-A Ultrathin porphyrin-based benzamide derivative HOFs nano material and preparation method and application thereof 河南大学 2023-12-15 CN claimed
CN-107880545-B Resin composition, method for producing cured product, and cured product 东京应化工业株式会社 2022-03-18 CN claimed
US-9851636-B2 Materials and methods for improved photoresist performance TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2017-12-26 US claimed
CN-103641820-B Tetrazolium imines coumarins copper ion fluorescence probe and preparation method thereof NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-01-20 CN claimed
CN-103641820-A Tetrazolium imine coumarins copper ion fluorescence probe and preparation method thereof UNIV NANJING SCIENCE & TECH 2014-03-19 CN claimed
EP-1117002-B1 Negative-working resist composition FUJIFILM CORP (JP) 2010-04-14 EP claimed
US-20060264357-A1 Capillary membrane stabilization and reduction of tissue injury through use of biodegradable macromolecules with antioxidants and/or other chemicals ZIKRIA BASHIR A 2006-11-23 US claimed
US-20060127387-A1 Compositions based on polysaccharides and protein C and methods of using the same for preventing and treating sepsis and other conditions ZIKRIA BASHIR A 2006-06-15 US claimed
EP-1343497-A4 $g(D)?2 ,-1,2,3-TRIAZOLINE ANTICONVULSANTS AND THEIR ACTIVE METABOLITE ANALOGUES, THE AMINOALKYLPYRIDINES, ARE EXCITATORY AMINO ACID ANTAGONISTS AND ANTIISCHEMIC AGENTS, USEFUL IN THE TREATMENT OF CEREBRAL ISCHEMIA RESULTING FROM STROKE K AND K BIOSCIENCES INC (US) 2005-01-26 EP claimed
US-20040073039-A1 Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke K AND K BIOSCIENCES, INC. 2004-04-15 US claimed
US-6699635-B1 SUITABLE FOR THE CASES WHEREIN FAR ULTRAVIOLET RAYS HAVING WAVELENGTHS OF 250 NM OR SHORTER ARE USED AS EXPOSURE LIGHT FUJI PHOTO FILM CO., LTD. (JP) 2004-03-02 US claimed
US-6673512-B1 PHOTORESISTS COMPRISING HOMO(CO)POLYCARBONS, ACID GENERATORS, CURING AGENTS AND BASES, USED TO FORM MINIATURIZED PATTERNS ON SEMICONDUCTORS USING X-RAYS OR RADIATION BEAMS; HIGH SENSITIVITY AND RESOLUTION FUJI PHOTO FILM CO., LTD. (JP) 2004-01-06 US claimed
EP-1343497-A1 $g(D)?2 ,-1,2,3-TRIAZOLINE ANTICONVULSANTS AND THEIR ACTIVE METABOLITE ANALOGUES, THE AMINOALKYLPYRIDINES, ARE EXCITATORY AMINO ACID ANTAGONISTS AND ANTIISCHEMIC AGENTS, USEFUL IN THE TREATMENT OF CEREBRAL ISCHEMIA RESULTING FROM STROKE K and K Biosciences, Inc. (US) 2003-09-17 EP claimed
US-20020111371-A1 Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke K AND K BIOSCIENCES, INC. 2002-08-15 US claimed
WO-2002036119-A1 Δ2,-1,2,3-TRIAZOLINE ANTICONVULSANTS AND THEIR ACTIVE METABOLITE ANALOGUES, THE AMINOALKYLPYRIDINES, ARE EXCITATORY AMINO ACID ANTAGONISTS AND ANTIISCHEMIC AGENTS, USEFUL IN THE TREATMENT OF CEREBRAL ISCHEMIA RESULTING FROM STROKE K AND K BIOSCIENCES, INC. (US) 2002-05-10 WO claimed
US-6083964-A ANTIEPILEPTIC PHARMACEUTICAL COMPOSITIONS WITH NO NEUROTOXICITY K AND K BIOSCIENCES, INC. (US) 2000-07-04 US claimed
US-5545307-A Process for patterned electroplating INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-08-13 US claimed
US-4292185-A COMPRISING A DIENE-MODIFIED MONOOLEFINIC POLYMER REACTED WITH CHLOROSULFONYL ISOCYANATE AND THEN WITH AN AMINE ROHM AND HAAS COMPANY (US) 1981-09-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073039-A1 Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke SIGMAR1, GRM1, GRIN2C SLC6A2 1753/4885SLC6A4 1735/4885SLC6A3 986/4885
US-20060127387-A1 Compositions based on polysaccharides and protein C and methods of using the same for preventing and treating sepsis and other conditions PROC, PYGM, FGB SLC6A2 4572/4885SLC6A4 4714/4885SLC6A3 4045/4885
US-20020111371-A1 Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke SIGMAR1, GRM1, GRIN2C SLC6A2 1753/4885SLC6A4 1735/4885SLC6A3 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.