Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26217825 | 0.85 | CYP1A2 (0.41) | ROCK2ROCK1KLKB1MEN1KMT2A | |
| SCHEMBL24863415 | 0.85 | ROCK2 (0.49) | ROCK2ROCK1KLKB1 | |
| SCHEMBL24863529 | 0.85 | KLKB1 (0.46) | KLKB1MEN1KMT2A | |
| SCHEMBL29788849 | 0.83 | NPSR1 (0.43) | ROCK2ROCK1KMT2A | |
| SCHEMBL15983143 | 0.78 | ROCK2 (0.42) | ROCK2ROCK1KLKB1MEN1KMT2A | |
| SCHEMBL18901136 | 0.77 | ROCK2 (0.41) | ROCK2ROCK1KLKB1MEN1KMT2A | |
| SCHEMBL29835991 | 0.76 | GAA (0.46) | ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL4395979 | 0.76 | GAA (0.46) | ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL23417918 | 0.75 | ALDH1A1 (0.58) | — | |
| SCHEMBL5723907 | 0.75 | MTNR1A (0.56) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814371-B2 | Heterocyclic compound | MEDSHINE DISCOVERY INC. (CN) | 2023-11-14 | — | — | US | disclosed |
| EP-4116299-A1 | HETEROCYCLIC COMPOUND | Medshine Discovery Inc. (CN) | 2023-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814371-B2 | Heterocyclic compound | CYP11B2, CYP4F11, CYP11B1 | ROCK2 3794/4885ROCK1 3246/4885KLKB1 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.