SCHEMBL29342074 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KLKB1	P03952	1/20	0.42

▸	FURIN	P09958	7/20	0.41

▸	PDF	Q9HBH1	1/20	0.41

▸	PLG	P00747	1/20	0.39

▸	CALCRL	Q16602	1/20	0.38

▸	TERT	O14746	1/20	0.38

▸	SSTR3	P32745	1/20	0.37

▸	CA1	P00915	1/20	0.37

▸	CA2	P00918	1/20	0.37

▸	MMP3	P08254	1/20	0.36

▸	NMT2	O60551	1/20	0.36

▸	NMT1	P30419	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24864487	0.92	KLKB1 (0.44)	KLKB1FURINPDFPLGCALCRL
SCHEMBL27291534	0.85	FURIN (0.48)	KLKB1FURINPDFPLGCALCRL
SCHEMBL15686242	0.83	NMT2 (0.45)	KLKB1FURINPDFPLGCALCRL
SCHEMBL16645085	0.83	FURIN (0.45)	KLKB1FURINPDFPLGCALCRL
SCHEMBL29342070	0.82	FURIN (0.42)	KLKB1FURINPDFPLGSSTR3
SCHEMBL24864663	0.81	KLKB1 (0.48)	KLKB1PDFPLGCALCRLSSTR3
SCHEMBL29342079	0.81	TERT (0.57)	TERT
SCHEMBL17661798	0.80	FURIN (0.42)	KLKB1FURINPDFPLGCALCRL
SCHEMBL14978855	0.80	NMT2 (0.45)	KLKB1FURINCALCRLNMT2NMT1
SCHEMBL15692124	0.80	NMT2 (0.45)	KLKB1FURINCALCRLNMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024151890-A1	LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME	PROFOUNDBIO US CO. (US)	2024-07-18	—	—	WO	disclosed