Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 6/20 | 0.42 |
| ▸ | Q9HBH1 | 1/20 | 0.42 | |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29342074 | 0.92 | KLKB1 (0.42) | KLKB1FURINPDFPLGCALCRL | |
| SCHEMBL24864633 | 0.85 | QRFPR (0.38) | FURINITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL15686242 | 0.85 | NMT2 (0.45) | KLKB1FURINPDFPLGCALCRL | |
| SCHEMBL16645085 | 0.85 | FURIN (0.45) | KLKB1FURINPDFPLGCALCRL | |
| SCHEMBL27291534 | 0.85 | FURIN (0.48) | KLKB1FURINPDFPLGCALCRL | |
| SCHEMBL24864663 | 0.82 | KLKB1 (0.48) | KLKB1PDFPLGCALCRLSSTR3 | |
| SCHEMBL17661798 | 0.81 | FURIN (0.42) | KLKB1FURINPDFPLGCALCRL | |
| SCHEMBL14978855 | 0.81 | NMT2 (0.45) | KLKB1FURINCALCRLNMT2NMT1 | |
| SCHEMBL15692124 | 0.81 | NMT2 (0.45) | KLKB1FURINCALCRLNMT2NMT1 | |
| SCHEMBL29345943 | 0.81 | FURIN (0.42) | KLKB1FURINPDFPLGITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |