Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | Q9HBH1 | 1/20 | 0.41 | |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686242 | 0.94 | NMT2 (0.45) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL16645118 | 0.89 | FURIN (0.47) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL17661798 | 0.88 | FURIN (0.42) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL14978855 | 0.85 | NMT2 (0.45) | FURINCALCRLKLKB1CTSLNMT2 | |
| SCHEMBL15692124 | 0.85 | NMT2 (0.45) | FURINCALCRLKLKB1CTSLNMT2 | |
| SCHEMBL16274147 | 0.85 | FAP (0.38) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL24864487 | 0.85 | KLKB1 (0.44) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL20332469 | 0.85 | CA2 (0.45) | FURIN | |
| SCHEMBL29335395 | 0.84 | KLKB1 (0.43) | FURINCALCRLKLKB1PLGPDF | |
| SCHEMBL15699715 | 0.83 | FURIN (0.39) | FURINCALCRLKLKB1CTSLNMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849191-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | FURIN 3298/4885CALCRL 3765/4885KLKB1 3486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.